Lymphoreticular malignancies are more common in patients with hemophilia, but it is usually attributed to human immunodeficiency virus (HIV) infection associated with repeated use of blood products. However, there are a couple of hemophiliac patients with malignancies but without HIV infection in the literature. We report a case of a hemophiliac patients who had Hodgkin's disease at 2.3 years old without any congenital or acquired immunodeficiency and without use of any blood products. This patient showed that malignancy can develop in hemophiliacs without HIV infection, but further studies are needed to clarify whether hemophiliacs are more susceptible to malignancies.