Abstract
Serum erythropoietin (EPO) and granulocyte-macrophage-colony stimulating factor (GM-CSF) levels were determined in 12 children with acute and seven with chronic idiopathic thrombocytopenic purpura (ITP) prior to and during megadose methylprednisolone (MDMP) treatment by using enzyme-linked immunosorbant assay (ELISA) kits. It was shown that elevation of EPO and GM-CSF levels was correlated with an increase in hemoglobin (Hb), packed cell volume (PCV), red blood cell (RBC), leukocyte (Leu), polymorphonuclear leukocyte (PMN) and monocyte (Mo) counts during MDMP treatment.
Copyright and license
Copyright © 1996 The Author(s). This is an open access article distributed under the Creative Commons Attribution License (CC BY), which permits unrestricted use, distribution, and reproduction in any medium or format, provided the original work is properly cited.