Abstract
A family with the Holt-Oram syndrome is described; both the proband and her father had unusually severe upper extremity malformations. The clinical, cardiologic and dermatoglyphic findings of the proband and the family members are discussed and the relevant literature is cited for comparison and contrast. This case is apparently more severe than others of the kind so far to have been reported.
Keywords: amelia, congenital malformation, Holt-Oram syndrome, phocomelia
Copyright and license
Copyright © 1985 The Author(s). This is an open access article distributed under the Creative Commons Attribution License (CC BY), which permits unrestricted use, distribution, and reproduction in any medium or format, provided the original work is properly cited.
