A review of the literature concerning Wilms' tumor is presented, followed by a description of various treatments for the disease, concluding that Actinomycin D with x-ray irradiation has proved the most successful to date.

Thirty-nine patients with Wilms' tumor, some of whom also showed distant metastases, were treated at Hacettepe Hospital between 1957 and 1966, by nephrectomy and radiotherapy, or nephrectomy, radiotherapy and Actinomycin D (which became available in Turkey after 1962). The latter treatment was found to be far superior to former.