Abstract

Background. Primary breast lymphoma is extremely rare and constitutes approximately 1% of all non-Hodgkin’s lymphomas (NHL). Only 1-5% of them are Burkitt type. We present a case of childhood primary breast Burkitt lymphoma (BL).

Case presentation. A 16-year-old female patient was referred to our hospital for bilateral breast swelling and respiratory distress. She had lactic acidosis. Despite aggressive dialysis support, lactic acid levels started to decrease only after the combination chemotherapy treatment was started and returned to normal. Histopathological examination of the biopsy was consistent with the diagnosis of BL. The case was classified as stage 4 disease. EICNHL Mature B NHL protocol, Group C3 chemotherapy was given and a very good partial response was achieved. However, the patient died due to fungal septicemia.

Conclusion. Type B lactic acidosis in aggressive malignancies indicates a poor prognosis. In such cases, as in our case, lactic acidosis improves only with appropriate and sufficient chemotherapy, and its improvement is an important indicator that the case is responsive to treatment.

Keywords: breast Burkitt lymphoma, lactic acidosis, childhood

Copyright and license

Copyright © 2024 The Author(s). This is an open access article distributed under the Creative Commons Attribution License (CC BY), which permits unrestricted use, distribution, and reproduction in any medium or format, provided the original work is properly cited.

How to cite

1.
Müngen E, Kurucu N, Kutluk T, Özcan HN, Kesici S, Orhan D. Primary breast Burkitt lymphoma with lactic acidosis in a child: a case report. Turk J Pediatr 2024; 66: 781-785. https://doi.org/10.24953/turkjpediatr.2024.4681

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