Abstract
The relationship between coagulation factors and the spleen was investigated. The data suggest that factor VIII and other coagulation factors (F I, II, V, VII/X, X) are not synthesized in the spleen. However the spleen has a storage function for F VIII and some other factors such as F II, V, VII/X, X. It has also been found that anesthesia has no effect on the levels of the coagulation factors.
Keywords: coagulation, factors VIII, II, VII/X, X, V, spleen function
Copyright and license
Copyright © 1982 The Author(s). This is an open access article distributed under the Creative Commons Attribution License (CC BY), which permits unrestricted use, distribution, and reproduction in any medium or format, provided the original work is properly cited.
